A.I & Neuroscience

AI와 신경과학의 교차점. 뇌과학 연구, 신경기술, 인지과학 최신 소식

최신 글

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Same Lock, Different Effects: Why LSD Is Psychedelic and Lisuride Isn't

LSD and lisuride occupy the same pocket of the human serotonin 2A receptor, 0.12 Å apart. Only LSD is psychedelic. We compared five published crystal structures residue by residue, checked the LSD pose against an independent structure from another lab, and went through what the literature says explains the difference.

10/9

니코틴은 왜 끊기 어려울까 — 실제 수용체 구조가 보여주는 것

사람 α4β2 니코틴성 수용체의 공개 cryo-EM 구조 두 개(니코틴 결합, 아세틸콜린 결합)를 직접 겹쳐 봤다. 세 주머니 모두에서 두 분자는 약 1Å 거리에 겹친다. 이것이 보여주는 것과 보여주지 못하는 것을 정리한다.

10/3

Why Is Nicotine So Hard to Quit? What the Real Receptor Structures Show

We overlaid two published cryo-EM structures of the human α4β2 nicotinic receptor, one holding nicotine and one holding acetylcholine. In all three pockets the two molecules sit about 1 Å apart. Here is what that shows, and what it doesn't.

10/3

사람 뇌 지도에서 뉴런 하나를 따라가 봤다 — 방법, 숫자, 그리고 우리가 틀렸던 것

공개된 H01 사람 대뇌피질 커넥톰을 열어 5층 추체세포 하나에 들어오는 입력을 전부 셌다. 시냅스 6,131개, 축삭 조각 4,761개. 영상에서 다 못 한 방법·그림·한계를 정리한다.

10/1

We Followed One Neuron Through a Map of the Human Brain — Methods, Numbers, and What We Got Wrong

We opened the public H01 human-cortex connectome and counted every input to a single layer-5 pyramidal neuron: 6,131 synapses from 4,761 axon segments. Here are the methods, the figures, and the caveats our video could only hint at.

10/1

Does Chronic Stress Really Lower Hippocampal BDNF? What an LLM Read of 9,585 Studies Actually Says

A plain-language companion to our preprint: an LLM extracted structured data from 9,585 stress–brain studies and found hippocampal BDNF reported down and up about equally, neuroinflammation overtaking the HPA axis since ~2018, and a structural-vs-functional split behind the amygdala contradiction.

6/5